This call seeks proposals for development of projects supported under NBM and BIRAC schemes falling under:
1. Biosimilars
2. Bio-betters including antibodies and recombinant proteins
3. Novel antibody-based biotherapeutics including monoclonal antibody and antibody fragments (Fab, Fv, ScFv), Nanobodies, cell and gene therapy, antibody drug conjugates
4. Expansion of existing facilities without any civil/ construction work, to increase the service portfolio.
5. Platforms developed and requiring validation with industry 6. Validation and scale-up of Raw Materials
Expectation from Applicant
1. The applicant should be a BIRAC grantee and should have previous funded project ongoing/completed for which the follow-on funding is sought
2. The earlier project should have been successfully completed with clear achievements on deliverables
3. The proposal should be built up on the previous results and activities and have a clear development path
4. The proposal should show progress of at least 2 TRL levels beyond the current stage
5. The therapeutic candidate should have substantial improvement over marketed products. The areas of improvement could be improved specificity, efficacy, potency, half-life, immunogenicity, reduced toxicity and side effects, affordability as compared to existing therapeutics.
6. For shared facilities justification and need for expansion and support required should be elaborated. The current test services, comparative pricing compared to international agencies, pricing model for academia, start-ups, MSMEs, large Indian Companies International companies to be given in proposal. The extent of differential pricing based on BIRAC financial support to be mentioned
The proposals can be submitted:
1. The applicant should be a BIRAC grantee and should have previous funded project ongoing/completed for which the follow-on funding is sought
2. Solely by Indian Company / LLP/ Non-profit organizations/ Society/ Trusts/ Foundation/ Associations/ Government entities/ Institutes/ R&D Organizations/ which is a legal entity OR Jointly by Indian Companies/ Non-profit organizations / LLP/ Society/ Trusts/ Foundation/ Associations/ Government entities/ Institutes/ R&D Organizations/ OR
3. By an -academia consortium of Indian Company/ Non-profit organizations/ LLP/ Society/ Trusts/ Foundation/ Association/ Government entities/ Institutes/ R&D Organizations
4. Indian Start-up companies in collaboration with Industry/Academia/research institutes/ are specially encouraged to apply.